Biochemistry Question Bank Sem-2 B.Pharm

This Biochemistry Question Bank Describe contains all the important questions from the syllabus of biochemistry in the format of 10, 5, and 2 marks.

10 marks long essay

1. Describe the reactions involved in the de novo biosynthesis of fatty acids.
2. Explain the Biosynthesis of proteins in the body.
3. Define gluconeogenesis and explain the reactions involved and its Significance.
4. Mention the types of RNA. Explain their role in protein synthesis.
5. Explain the TCA cycle and give its significance with energies.
6. Explain the degradation of heme and add a note on different types of jaundice.
7. Explain the biosynthesis of pyrimidine nucleotides in the body.
8. Describe the ß-Oxidation of palmitic acid along with the energetics.
9. Explain glycolysis and its energetics.
10. Describe the de novo biosynthesis of purine nucleotides.
11. Define and explain the reaction sequences of glycolysis and its energetics.
12. Explain the semiconservative replication of DNA in detail.
13. Explain the process of ß-Oxidation of fatty acids with energetics. Considering palmitic acid as an example.
14. Explain the various reactions involved in the Citric acid cycle.
15. What are the requisites for protein synthesis? Explain the steps involved In Protein synthesis.
16. Explain the de novo biosynthesis of fatty acids along with the enzyme system involved.
17. Explain the general reactions involved in the metabolism of amino acids.
18. Explain the various reactions involved in the Krebs cycle with energetics.

5 marks short essay

1. Explain the different types of RNA.
2. Explain the synthesis of bile acids.
3. What is substrate level phosphorylation and oxidative phosphorylation?
4. Give the Amphibolic Nature and energetics of the TCA cycle.
5. Explain the double helical structure of DNA.
6. Explain glycogen storage disease.
7. Describe the biosynthesis of pyrimidine bases.
8. Give the reaction sequence in the HMP shunt.
9. Write the metabolism of purine nucleotides.
10. Write the formation of ketone bodies in the body.
11. Explain ketolysis with significance.
12. Explain the electron transport chain.
13. Describe the structure and functions of tRNA.
14. Define enzyme inhibition and discuss any one type of enzyme inhibition.
15. Define energy-rich compounds and classify them with suitable examples.
16. Explain the energy-investing reactions of glycolysis.
17. Give the salient features of the Genetic code.
18. Define enzymes, and classify them according to IUB.
19. Define coenzymes and discuss different types of coenzymes.
20. Explain the semi-conservative mode of replication of DNA.
21. Explain the chemo osmatic theory of oxidative phosphorylation.
22. Explain the competitive enzyme inhibition with examples.
23. How ketone bodies formed.
24. Describe the hormonal regulation of blood glucose levels.
25. Give Structure and biological significance of ATP and Cyclic AMP.
26. Give the significance of cholesterol, How it gets converted to bile acids
27. Explain Glycogenesis and Glycogenolysis.
28. Define coenzymes, Give the structure and biological role of coenzyme NAD and FAD.
29. Describe the HMP pathway and its significance.
30. Write the formation of ketone bodies in the body.
31. Explain the biologically important compounds obtained from cholesterol.
32. Describe the process of transcription.
33. Explain the structure and functions of t-RNA.
34. Define carbohydrates and classify them with examples and their biological significance.
35. Explain glycogen storage disease.
36. Write the catabolism of purine Nucleotides.
37. Define genetic code and give its salient futures.
38. Explain the competitive enzyme inhibition with examples.
39. Define oxidative and substrate-level phosphorylation.
40. Define coenzymes; Give the structure and functions of NAD And FAD.
41. Define enzyme. Give IUB classification of enzymes with examples.
42. Givè chemical classification of amino acids.
43. Explain gluconeogenesis with reactions involved in it and write its Importance.
44. Describe the double helical structure of DNA.
45. Explain disorders of lipid metabolism.
46. Define Enthalpy and Entropy. Explain the relation between them.

2 marks short essay

1. Define isoenzyme with examples.
2. What is the role of carnitine in fatty acid metabolism?
3. What are the denaturation and renaturation of proteins?
4. Name chain terminating codons.
5. What are isoenzymes? Give examples.
6. Name the essential amino acids
7. What is the B-Oxidation of fatty acids?
8. Write the uncouplers of ETC.
9. Write four differences between DNA and RNA.
10. Define energy-rich compounds with examples.
11. What is ketosis?
12. What are cofactors? Give examples.
13. Name bile pigments, and bile salts. What is galactosuria ? Name the enzyme involved in it.
14. Give the structures of any two essential fatty acids.
15. What are holoenzymes? Give examples.
16. What is atherosclerosis?
17. Write the inhibitors of ETC.
18. Name the different types of jaundice.
19. Write any two biochemical functions of cholesterol.
20. What are lipotropic factors? Name them.
21. Give the therapeutic importance of enzymes.
22. Write the types of diabetic mellitus.
23. Name different types of porphyrias
24. Define nucleosides and nucleotides.
25. What is Gout?
26. Name the glucogenic amino acids.
27. Define Km and write its significance.
28. Mention the bases of DNA and RNA
29. Name the enzymes and coenzymes present in the pyruvate dehydrogenase Complex.
30. What are Okazaki fragments?
31. What is alkaptonuria
32. Write the biological significance of proteins.
33. Define enzyme induction and repression
34. Give the Amphibolic Nature of the Krebs cycle.
35. Name the essential amino acids.
36. What is hyperbilirubinemia?
37. Define nucleosides and nucleotides
38. Write the significance of the line weaver Burk plot.
39. What is an isoelectric point?
40. Define free energy and redox potential.
41. Write four differences between DNA and RNA.
42. Write the structure and biochemical functions of cyclic AMP.
43. Define essential fatty acids with examples.
44. Give the physicochemical functions of serotonin.
45. What is phenylketonuria?
46. What are the functions of t-RNA
47. Write the biological functions of proteins.
48. Name the bile salts and give their significance
49. Name the ketogenic amino acids.
50. Amphibolic Nature of TCA cycle.
51. Write the biological significance of proteins.
52. Define V max and write its significance