Pharmaceutical chemistry is the study of drugs, and it involves drug development. This includes drug discovery, delivery, absorption, metabolism, and more. There are elements of biomedical analysis, pharmacology, pharmacokinetics, and pharmacodynamics.
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According to the syllabus of 2023 by PCI (Pharmacy Council of India), you will get the link to download all the handwritten and standard notes, you get the option to download all the notes semester wise or unit wise.
1. Introduction to Pharmaceutical Chemistry
Scope and objectives
Sources and types of errors: Accuracy, precision, significant figures
Impurities in Pharmaceuticals: Source and effect of impurities in Pharmacopoeial substances, importance of limit test, Principle and procedures of Limit tests for chlorides, sulphates, iron, heavy metals and arsenic.
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Chapter 2
1. Volumetric analysis
Fundamentals of volumetric analysis, Acid-base titration, non-aqueous titration, precipitation titration, complexometric titration, redox titration
Gravimetric analysis: Principle and method.
Chapter 3
1. Inorganic Pharmaceuticals
Pharmaceutical formulations, market preparations, storage conditions and uses of
Haematinics: Ferrous sulphate, Ferrous fumarate, Ferric ammonium citrate, Ferrous ascorbate, Carbonyl iron
Gastro-intestinal Agents: Antacids :Aluminium hydroxide gel, Magnesium hydroxide, Magaldrate, Sodium bicarbonate, Calcium Carbonate, Acidifying agents, Adsorbents, Protectives, Cathartics
Topical agents: Silver Nitrate, Ionic Silver, Chlorhexidine Gluconate, Hydrogen peroxide, Boric acid, Bleaching powder, Potassium permanganate
Dental products: Calcium carbonate, Sodium fluoride, Denture cleaners, Denture adhesives, Mouth washes
Medicinal gases: Carbon dioxide, nitrous oxide, oxygen
Chapter 4
Introduction to nomenclature of organic chemical systems with particular reference to heterocyclic compounds containing up to Three rings
Chapter 5
1. Drugs Acting on Central Nervous System
Anaesthetics: Thiopental Sodium, Ketamine Hydrochloride, Propofol
Sedatives and Hypnotics: Diazepam, Alprazolam, Nitrazepam, Phenobarbital*
Antipsychotics: Chlorpromazine Hydrochloride, Haloperidol, Risperidone, Sulpiride, Olanzapine, Quetiapine, Lurasidone
Anticonvulsants: Phenytoin, Carbamazepine, Clonazepam, Valproic Acid, Gabapentin, Topiramate, Vigabatrin, Lamotrigine
Anti-Depressants: Amitriptyline Hydrochloride, Imipramine Hydrochloride, Fluoxetine*, Venlafaxine, Duloxetine, Sertraline, Citalopram, Escitalopram, Fluvoxamine, Paroxetine
Chapter 6
1. Drugs Acting on Autonomic Nervous System
Sympathomimetic Agents: Direct Acting: NorEpinephrine*, Epinephrine, Phenylephrine, Dopamine, Terbutaline, Salbutamol (Albuterol), Naphazoline, Tetrahydrozoline.
Indirect Acting Agents: Hydroxy Amphetamine, Pseudoephedrine. Agents With Mixed Mechanism: Ephedrine, Metaraminol
Adrenergic Antagonists: Alpha Adrenergic Blockers: Tolazoline, Phentolamine
Phenoxybenzamine, Prazosin. Beta Adrenergic Blockers: Propranolol, Atenolol, Carvedilol
Cholinergic Drugs and Related Agents: Direct Acting Agents: Acetylcholine, Carbachol, And Pilocarpine. Cholinesterase Inhibitors: Neostigmine, Edrophonium Chloride, Tacrine Hydrochloride, Pralidoxime Chloride, Echothiopate Iodide
Cholinergic Blocking Agents: Atropine Sulphate, Ipratropium Bromide Synthetic Cholinergic Blocking Agents: Tropicamide, Cyclopentolate Hydrochloride, Clidinium Bromide, Dicyclomine Hydrochloride
Chapter 7
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1. Drugs Acting on Cardiovascular System
Anti-Arrhythmic Drugs: Quinidine Sulphate, Procainamide Hydrochloride, Verapamil, Phenytoin Sodium, Lidocaine Hydrochloride, Lorcainide Hydrochloride, Amiodarone and Sotalol
Anti-Hypertensive Agents: Propranolol, Captopril*, Ramipril, Methyldopate Hydrochloride, Clonidine Hydrochloride, Hydralazine Hydrochloride, Nifedipine,
Antianginal Agents: Isosorbide Dinitrate
Chapter 8
Diuretics: Acetazolamide, Frusemide*, Bumetanide, Chlorthalidone, Benzthiazide, Metolazone, Xipamide, Spironolactone
Chapter 9
Hypoglycemic Agents: Insulin and Its Preparations, Metformin, Glibenclamide, Glimepiride, Pioglitazone, Repaglinide, Gliflozins, Gliptins
Chapter 10
Analgesic And Anti-Inflammatory Agents: Morphine Analogues, Narcotic Antagonists;
Nonsteroidal AntiInflammatory Agents (NSAIDs) – Aspirin, Diclofenac, Ibuprofen, Piroxicam, Celecoxib, Mefenamic Acid, Paracetamol*, Aceclofenac
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