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Pharmaceutical Biotechnology contains
Brief introduction to Biotechnology with reference to Pharmaceutical Sciences.
Enzyme Biotechnology- Methods of enzyme immobilization and applications.
Biosensors- Working and applications of biosensors in Pharmaceutical Industries.
Brief introduction to Protein Engineering.
Use of microbes in industry. Production of Enzymes- General consideration – Amylase, Catalase, Peroxidase, Lipase, Protease, Penicillinase.
Basic principles of genetic engineering.
Study of cloning vectors, restriction endonucleases and DNA ligase.
Recombinant DNA technology. Application of genetic engineering in medicine.
Application of r DNA technology and genetic engineering in the production of:
i) Interferon ii) Vaccines- hepatitis- B iii) Hormones-Insulin.
Brief introduction to PCR.
Types of immunity- humoral immunity, cellular immunity
Structure of Immunoglobulins
Structure and Function of MHC
Hypersensitivity reactions, Immune stimulation and Immune suppressions.
General method of the preparation of bacterial vaccines, toxoids, viral vaccine, antitoxins, serum-immune blood derivatives and other products relative to immunity.
Storage conditions and stability of official vaccines
Hybridoma technology- Production, Purification and Applications
Blood products and Plasma Substituties.
Immuno blotting techniques- ELISA, Western blotting, Southern blotting.
Genetic organization of Eukaryotes and Prokaryotes
Microbial genetics including transformation, transduction, conjugation, plasmids and transposons.
Introduction to Microbial biotransformation and applications.
Mutation: Types of mutation/mutants.
Fermentation methods and general requirements, study of media, equipments, sterilization methods, aeration process, stirring.
Large scale production fermenter design and its various controls.
Study of the production of – penicillins, citric acid, Vitamin B12, Glutamic acid, Griseofulvin,
Blood Products: Collection, Processing and Storage of whole human blood, dried human plasma, plasma Substituties.
ASIN : B0B18JY1CW
Publisher : TECHNICAL PUBLICATIONS; 1st edition (12 May 2022)
Language : English
File size : 10901 KB
Text-to-Speech : Not enabled
Enhanced typesetting : Not Enabled
X-Ray : Not Enabled
Word Wise : Not Enabled
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